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Skin Conditioning

HEDERACOLCHISIDE

CAS 106577-39-3
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An ivy-derived saponin with antioxidant and anti-inflammatory studies, but cytotoxic at higher doses. Cosmetic-specific safety data are thin.

Function

SKIN CONDITIONING

Skin benefits

  • Saponin-derived antioxidant
  • Anti-inflammatory in animal models
  • Hedera-derived skin tonic

Known concerns

  • Saponin cytotoxicity to cancer cells in vitro suggests dose caution
  • Limited cosmetic-grade safety dossier
  • Hederacolchiside A1 induces apoptosis

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.