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Fragrance

HEPTADIENAL

CAS 4313-03-5
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A conjugated dienal — chemically very similar to 2,4-hexadienal in reactivity. Skin sensitizer class; not appropriate for leave-on cosmetics.

Heptadienal (CAS 4313-03-5, likely 2,4-heptadienal) is a short-chain doubly-conjugated α,β-unsaturated aldehyde. This functional group class is highly reactive toward skin protein thiols and amines (Michael addition), which underlies the documented skin sensitization and irritation profile of sibling compounds like 2,4-hexadienal and 2,4-decadienal. GHS classifications typically include acute oral toxicity, skin irritation, serious eye damage, and skin sensitization. Cosmetic-specific CIR/SCCS monographs are lacking. Industry practice is to avoid this class in leave-on cosmetic products; trace flavor occurrence in food is a different regulatory context.

Function

PERFUMING

Skin benefits

  • Trace fatty-green note

Known concerns

  • Reactive conjugated dienal
  • Skin sensitizer class
  • Irritation
  • Unsuitable for leave-on cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related fragrances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.