Hexaethyl tetraphosphate
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Hexaethyl Tetraphosphate is a cosmetic ingredient. Exercise caution due to limited available safety data.
Hexaethyl tetraphosphate is an organophosphate ester historically used as a plasticiser and flame retardant. The tetraphosphate structure indicates potent cholinesterase inhibition, analogous to parathion-type insecticides. REACH Annex XVII restrictions prohibit use above 0.1% in mixtures, effectively eliminating cosmetic use. The EU cosmetics regulation independently prohibits substances subject to SVHC identification.
Known concerns
- SVHC under REACH: prohibited in cosmetics above 0.1%
- Cholinesterase inhibition: neurotoxicity concern
- No safe use level established for cosmetic application
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.