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HEXAHYDRO-METHANOINDEN-6-YL-ISOPENTENOL

CAS 126646-06-8
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hexahydro-methanoinden-6-yl-isopentenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Hexahydro-methanoinden-6-yl-isopentenol (also known under trade names such as Sandalore or similar woody aroma chemicals) is a synthetic fragrance ingredient. Its chemical structure contains a bicyclic sesquiterpenic core with an isopentenyl side chain. The fragrance community (IFRA/RIFM) has assessed this class for phototoxicity and sensitisation. The primary concern is that unsaturated sesquiterpenic structures can oxidise on air exposure, forming sensitisers such as hydroperoxides. Standard IFRA recommendations restrict oxidized material. Not listed on EU Annex II or III, suggesting it is not a confirmed high-concern restricted substance — hence the score in the 60s.

Skin benefits

  • Provides woody, amber fragrance notes in cosmetic formulations

Known concerns

  • Fragrance allergen — potential for skin sensitisation upon oxidation
  • Unsaturated structure — forms sensitisers on air exposure
  • IFRA restrictions apply to oxidized material
  • Limited repeat-dose toxicity data in public literature

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.