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Preservative

HEXAMIDINE

CAS 3811-75-4 Updated
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cationic antimicrobial used at low concentrations to keep formulas microbially stable. Effective and EU-regulated, but it can sensitize a fraction of users.

Function

PRESERVATIVE

Skin benefits

  • Antimicrobial preservative
  • Effective against gram-positive bacteria and yeasts
  • Used in dermatological formulations
  • Skin-soothing claims at low %

Known concerns

  • Possible contact sensitization in some users
  • Cationic antimicrobial — irritant potential
  • Restricted use levels in EU cosmetics
  • Limited rinse-off vs leave-on data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.