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Hexane

CAS 110-54-3
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hexane is a cosmetic ingredient. Exercise caution due to limited available safety data.

n-Hexane is a aliphatic hydrocarbon solvent with recognized neurotoxic properties causing peripheral neuropathy and reproductive toxicity. Under EU REACH regulation, it is restricted at ≥0.1% in mixtures and is listed as a substance of very high concern (SVHC) due to its chronic neurotoxicity and reproductive effects, making it unsuitable for cosmetic formulations.

Known concerns

  • Neurotoxicity (peripheral neuropathy)
  • Reproductive toxicity
  • Restricted at ≥0.1% under REACH
  • Not permitted in cosmetic products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.