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Polymer Cross-linker

HEXANEDIOL DIMETHACRYLATE

CAS 6606-59-3
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A difunctional methacrylate cross-linker used in nail and dental products. Uncured monomer is a well-known skin sensitiser, so this is a clear orange-tier caution ingredient.

Function

NAIL CONDITIONING

Skin benefits

  • Cross-linker for nail and dental polymers
  • Builds durable cured films
  • Improves wear and chemical resistance

Known concerns

  • Difunctional methacrylate — strong skin sensitiser when uncured
  • Allergic contact dermatitis well documented
  • Eye and respiratory irritation potential
  • Not appropriate for skincare leave-ons

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.