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Skin Conditioning

HEXAPEPTIDE-12

CAS - Updated
85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic hexapeptide combining alanine, glycine, proline and valine residues, used in cosmetics for potential skin-smoothing and anti-ageing benefits. Clean low-irritation safety profile and no significant documented concerns.

Skin benefits

  • Six-amino-acid synthetic peptide for skin smoothing
  • Composed of alanine, glycine, proline and valine
  • Used in anti-ageing cosmetics
  • Well tolerated at cosmetic concentrations

Known concerns

  • Limited independent efficacy data
  • Activity is supplier and concentration dependent

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.