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Skin Conditioning

HEXAPEPTIDE-21

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A six-amino-acid signaling peptide marketed for anti-aging skin care. Like other cosmetic peptides, the topical concentration is too low to expect adverse effects; efficacy data is thin.

Function

SKIN CONDITIONINGSURFACTANT - CLEANSING

Skin benefits

  • Targeted skin signaling peptide
  • Skin conditioning at low cosmetic levels
  • Class-typical low irritation

Known concerns

  • Limited public safety/efficacy literature
  • Manufacturer-proprietary peptide
  • Pharmacologic activity unclear at topical doses

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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(ARTEMISIA SIEVERSIANA/DIMOCARPUS LONGANA) FLOWER/LEAF/STEM EXTRACT
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(ASPARAGUS COCHINCHINENSIS/LIRIOPE MUSCARI/REHMANNIA CHINENSIS) ROOT EXTRACT
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(VETIVERIA ZIZANOIDES ROOT/PUERARIA THUNBERGIANA FLOWER/LEAF/STEM) WATER
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1,3-Dihydroxy-2-propanone
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ABIES ALBA WOOD EXTRACT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.