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Skin Conditioning

HEXAPEPTIDE-33

CAS -
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A six-amino-acid synthetic peptide for skin conditioning. Safe at ppm levels but efficacy evidence is supplier-led.

Hexapeptide-33 is a proprietary synthetic six-amino-acid peptide used in cosmetics for skin conditioning and anti-aging positioning. Specific sequence details are supplier-held. Used at parts-per-million concentrations in serums and creams. Small synthetic peptides of this class are generally non-irritating and non-sensitizing. No independent SCCS or CIR review identified. No GHS hazard classification applies at cosmetic use levels. Efficacy claims rely on supplier studies rather than independent peer-reviewed trials.

Function

ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

Skin benefits

  • Synthetic hexapeptide used for skin conditioning
  • Low irritation profile typical of cosmetic peptides
  • Used at trace concentrations

Known concerns

  • Proprietary sequence with supplier-only efficacy data
  • No SCCS or CIR opinion
  • Topical peptide bioavailability debated

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.