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Cosmetic Peptide

HEXAPEPTIDE-63

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A short synthetic peptide used in anti-aging products to help skin feel firmer and smoother. Generally well tolerated, but independent proof of meaningful benefits is still limited.

Function

SKIN CONDITIONING

Skin benefits

  • Synthetic six-amino-acid peptide marketed for skin signaling
  • Designed to support firmness and smoothness
  • Low molecular weight allows some penetration into upper skin layers
  • Typically used at low percentages with minimal irritation

Known concerns

  • Independent clinical evidence for benefits is limited
  • Stability and bioavailability depend on formulation
  • Long-term safety data not well established
  • Marketing claims often outpace published research

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related cosmetic peptides

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.