Skip to content

Skin Conditioning

HEXAPEPTIDE-63

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic six-amino-acid peptide used at low concentrations for skin conditioning. Low-risk by class, specific evidence limited.

Hexapeptide-63 is a defined-sequence six-amino-acid synthetic peptide marketed for skin conditioning. Like other numbered hexapeptides, it is typically used at fractions of a percent in serums or treatment products. The peptide class shows favorable safety — low irritation, minimal sensitization, and enzymatic breakdown into amino acids. There is no published CIR or SCCS opinion specific to Hexapeptide-63. Peer-reviewed efficacy literature is essentially limited to supplier-generated in vitro and small-panel data. Considered low-risk, low-evidence.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning
  • Low irritation profile
  • Defined synthetic sequence

Known concerns

  • Limited independent data
  • No regulatory review
  • Supplier-driven efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

65
(ANGELICA GIGAS/CNIDIUM OFFICINALE/PAEONIA LACTIFLORA) ROOT EXTRACT
Skin Conditioning
 65
(SH-OLIGOPEPTIDE-78 S-FRUIT FLY OLIGOPEPTIDE-1) PEPTIDES
Skin Conditioning
 65
(SH-PENTAPEPTIDE-10 6-AMINOCAPROOYL SH-PENTAPEPTIDE-11) SP
Skin Conditioning
 65
ABELMOSCHUS MANIHOT CALLUS EXTRACELLULAR VESICLES
Skin Conditioning
 65
ABIES BALSAMEA EXTRACT
Skin Conditioning
 65
ACEFYLLINE METHYLSILANOL MANNURONATE
Skin Conditioning
 65
ACETAMINO METHYLSULFONYLBUTYROYL DIPEPTIDE-57
Skin Conditioning
 65
ACETYL HEPTAPEPTIDE-69
Skin Conditioning

Check your shelf

Find HEXAPEPTIDE-63 in your products.

Scan any cosmetic product with LuxSense to see if it contains HEXAPEPTIDE-63 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.