Skin Conditioning
HEXAPEPTIDE-80
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic six-amino-acid peptide used as a skin-conditioning agent. Modern designer peptide; trace-level use minimizes irritation but independent safety data is limited.
Hexapeptide-80 is a six-residue synthetic peptide developed for skin-conditioning use. As with most designer hexapeptides in cosmetic formulations, it is supplied dilute and typically used at parts-per-million concentrations. The class is considered low-irritation and low-systemic-risk due to poor penetration and rapid degradation, but Hexapeptide-80 lacks an independent CIR or SCCS review, and most efficacy data is supplier-sponsored. Listed in EU CosIng. Conservative classification is yellow with low evidence.
Function
Skin benefits
- Skin-conditioning at trace levels
- Compatible with sensitive-skin formats
- Low sensitization potential
Known concerns
- Sparse independent safety data
- No regulatory monograph
- Performance depends on supplier-side stability
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.