Skin Conditioning
HEXAPEPTIDE-88
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A synthetic six-amino-acid peptide used as a skin-conditioning agent. Modern designer peptide with limited independent safety literature; typically used at ppm levels.
Hexapeptide-88 is a synthetic six-residue peptide formulated for skin-conditioning use in serums and creams. Hexapeptides in cosmetic use are usually delivered at trace concentrations (often <0.001%) and are generally regarded as low-irritation, low-systemic-risk because of poor skin penetration and rapid surface degradation. Independent CIR or SCCS reviews of this specific INCI have not been published, and most efficacy data comes from supplier-sponsored testing. Listed in EU CosIng. Pending more independent safety and clinical literature, conservative classification is yellow with low evidence.
Function
Skin benefits
- Targeted skin-conditioning at trace levels
- Compatible with serum and cream bases
- Low sensitization profile in supplier testing
Known concerns
- Sparse independent safety data
- Supplier-controlled efficacy claims
- Stability sensitive to formulation pH and preservatives
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.