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HEXYL 3-GLYCERYL ASCORBATE

80

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A stable lipid-soluble vitamin C derivative offering antioxidant benefits and potential collagen support with better skin penetration than pure ascorbic acid.

Hexyl 3-glyceryl ascorbate is a hybrid ascorbate derivative where ascorbic acid is modified with both a hexyl chain and a glyceryl group to improve lipid solubility and skin penetration. This modification addresses the pH-dependence and instability of pure L-ascorbic acid. The compound retains the antioxidant properties and skin benefits of vitamin C while offering improved formulation flexibility. Like other ascorbate derivatives, it is not subject to EU cosmetic restrictions and is considered safe for use in skincare formulations.

Skin benefits

  • Stable antioxidant vitamin C delivery
  • Enhanced skin penetration vs pure ascorbic acid
  • Collagen synthesis support potential
  • Skin brightening

Known concerns

  • Generally very safe - limited concerns
  • Formulation-dependent stability

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.