Skip to content

Antimicrobial / preservative booster

HINOKITIOL

CAS 499-44-5
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Hinokitiol is a natural tropolone from hinoki cypress with antimicrobial, anti-inflammatory, and antioxidant properties. It is widely used in Asian skincare and oral care, with regulated maximum levels in finished products.

Skin benefits

  • Naturally occurring tropolone with antimicrobial activity
  • Used in oral care, scalp, and skin formulations against acne and dandruff
  • Has anti-inflammatory and antioxidant effects in lab studies

Known concerns

  • Strong metal-chelating activity may interact with mineral nutrition concerns at high exposure
  • Some animal studies suggest developmental effects at high doses
  • Use levels are regulated in some jurisdictions including Japan and EU

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related antimicrobial / preservative boosters

Check your shelf

Find HINOKITIOL in your products.

Scan any cosmetic product with LuxSense to see if it contains HINOKITIOL and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.