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Skin Conditioning

HISTIDINE HCL

CAS 645-35-2 / 5934-29-2 Updated
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Histidine, an essential amino acid, in its hydrochloride form. Native to skin, well buffered, and an effective mild antioxidant — one of the safest small-molecule conditioning agents.

Function

HAIR CONDITIONING, SKIN CONDITIONING

Skin benefits

  • Essential amino acid
  • Skin conditioning and antioxidant
  • Buffering capacity
  • Excellent biocompatibility

Known concerns

  • No significant concerns at cosmetic concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.