Skin Conditioning
HISTIDINE
Safety score · 0–100
Excellent
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An essential amino acid and natural part of skin's moisturizing factor (NMF). It hydrates, buffers pH, and offers mild antioxidant chelating activity. Excellent safety record at cosmetic levels.
Skin benefits
- Part of natural moisturizing factor (NMF)
- Antioxidant chelating activity
- Helps maintain skin pH balance
- Supports barrier function
Known concerns
- No significant concerns at cosmetic concentrations
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
PubChem
U.S. NIH compound data, GHS hazard codes and toxicity literature.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.