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HYDROLYZED CORN/SOY/WHEAT PROTEIN THIOGLYCOLAMIDE/THIOPROPIONAMIDE

52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A protein hydrolysate derivative incorporating thiol functional groups, used as a reducing agent in hair treatments, though it may cause skin sensitisation in susceptible individuals.

This ingredient is a hybrid protein-thiol compound derived from vegetable protein hydrolysates reacted with thiol-specific acylating agents. The presence of reactive thiol groups raises sensitisation potential, particularly for individuals with compromised skin barriers or thiol-specific allergies. EU Annex III does not list specific concentration limits for this material, but its reactive chemistry warrants caution and exclusion from leave-on facial products.

Skin benefits

  • May contribute to hair strengthening via disulfide bond formation
  • Can act as a reducing agent in oxidative hair treatments

Known concerns

  • Potential skin sensitisation due to reactive thiol groups
  • Limited long-term safety data available
  • Cross-reactivity possible with other protein-thiol derivatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.