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Antioxidant

HYDROXY TETRAMETHYLPIPERIDINE OXIDE

CAS 2226-96-2 Updated
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

TEMPOL — a nitroxide free-radical scavenger studied as a topical antioxidant. Pure raw material is irritating to eyes and may damage organs with prolonged exposure.

Function

ANTIOXIDANT

Skin benefits

  • Stable nitroxide free-radical scavenger
  • Antioxidant action in research formulas
  • Marketed for environmental defense

Known concerns

  • GHS H318 — causes serious eye damage at raw concentration
  • GHS H373 — possible organ effects with prolonged exposure
  • Limited CIR/SCCS opinion on cosmetic use
  • Stains-and-staining potential at high levels

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.