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Skin Conditioning

HYDROXYMETHYL PREGNACALCIFEROL

CAS 116499-21-9 Updated
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic vitamin D / pregnacalciferol analogue used in advanced skincare for renewal claims. Bioactive steroid-related chemistry warrants caution and patch testing.

Function

HUMECTANTSKIN CONDITIONINGSKIN PROTECTING

Skin benefits

  • Skin renewal claims
  • Conditioning

Known concerns

  • Steroid-related chemistry
  • Limited safety dossier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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ALBIZIA AMARA SEED EXTRACT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.