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HYDROXYMETHYLFURFURAL

CAS 67-47-0
50

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Hydroxymethylfurfural is a cosmetic ingredient. Exercise caution due to limited available safety data.

Hydroxymethylfurfural (HMF) is formed during the Maillard reaction and caramelization of sugars. It carries H315/H319/H335 (irritation) and H412 (aquatic toxicity with long-lasting effects) classifications. HMF is found naturally in many foods and is considered of low acute toxicity, but its presence in cosmetics (particularly those with sugar-derived ingredients) should be monitored. EU regulation 1223/2009 does not list specific restrictions for HMF but the compound is on ECHA's substance of concern registry.

Skin benefits

  • Found naturally in foods

Known concerns

  • Skin irritation (H315)
  • Eye irritation (H319)
  • Aquatic toxicity (H412)
  • May form in sugar-containing formulations during storage

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.