Antioxidant
HYDROXYPHENYL DIMETHOXYISOINDOLINONE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic isoindolinone antioxidant — it neutralizes free radicals in skin formulas. Specialty ingredient with limited public safety data, so we rank it cautious-yellow.
Hydroxyphenyl dimethoxyisoindolinone is a synthetic small-molecule antioxidant belonging to the isoindolinone class. It functions as a free-radical scavenger and photostabilizer in cosmetic formulations, typically at trace use levels (<1%). Unlike widely-studied antioxidants such as tocopherol or ascorbyl derivatives, this specific molecule does not appear with a full SCCS opinion or extensive CIR review in public regulatory databases. No IARC classification or GHS hazard profile identified at cosmetic-grade purity. Used in boutique anti-aging products; evidence base is thin and largely manufacturer-supplied.
Function
Skin benefits
- Antioxidant activity protecting against oxidative stress
- Photoprotective properties in skin formulations
- Stable across wide pH range
Known concerns
- Limited long-term human safety data
- Not on EU CosIng with full SCCS dossier
- Specialty ingredient with narrow safety literature
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related antioxidants
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.