Other
hydroxyprogesterone caproate
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
An esterified progestin with potent hormonal activity and developmental toxicity classification, absolutely prohibited in cosmetic products.
Hydroxyprogesterone caproate is the caproic acid ester of hydroxyprogesterone, used as a long-acting progestational agent in pharmaceutical formulations. The H360 signal word (Danger) indicates known reproductive/developmental toxicity. In the EU CosIng database, steroid hormone esters with documented H360 classification are explicitly banned under Annex II. This substance has no cosmetic application and represents a category 1B reproductive toxicant — completely incompatible with cosmetic formulation and sale within the EU market.
Known concerns
- H360 — known developmental and reproductive toxicity
- Category 1B CMR substance — Annex II banned
- Long-acting progestational agent with pharmaceutical classification
- No cosmetic use permitted in any EU member state
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.