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Colorant

Hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) and its tetrahydro-chloride

CAS 128729-30-6 -- 128729-28-2 Updated
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A bis-PPD style oxidative hair-dye precursor. EU regulates it under Annex III with strict use limits and warnings; classed as a strong skin sensitiser.

Skin benefits

  • Specific hair-dye shades

Known concerns

  • EU Annex III with strict % limits
  • p-Phenylenediamine class strong sensitiser
  • Allergic contact dermatitis risk

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.