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Colorant

HYDROXYPYRIDINONE

CAS 822-89-9
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A pyridinone heterocycle used as a hair-dye intermediate or chelator. Limited public safety data mean it gets a cautious, mid-range rating.

Hydroxypyridinone (the CAS 822-89-9 entry corresponds to 3-hydroxy-2(1H)-pyridinone / 2,3-dihydroxypyridine) is a nitrogen heterocycle used in several technical contexts — as an intermediate in oxidative hair dye couplers, and as a building block for iron-chelating chemistry (the deferiprone drug family). There is no public CIR Panel assessment, and while some closely related hydroxypyridinones have been characterised for drug use, the cosmetic-specific safety dossier is thin. In hair-dye matrices, sensitization risk comparable to other aromatic-amine couplers should be assumed. Chelation properties may interfere with cosmetic actives that rely on iron/copper (some vitamin C stabilisation strategies, for example). Default-down posture is warranted given the limited public data.

Skin benefits

  • Hair-dye intermediate role

Known concerns

  • Limited public cosmetic-safety dossier
  • Potential sensitization typical of hair-dye intermediates
  • Chelating properties may interact with other actives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.