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Cosmetic enzyme

HYDROXYSTEROID OXIDOREDUCTASE

CAS 9028-56-2
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An enzyme that interacts with hydroxysteroid molecules, sometimes used in advanced biotech skincare. Safety data is limited but the protein profile is low-risk at typical formulation levels.

Skin benefits

  • Enzyme of biotechnology origin used in niche cosmetic actives
  • Potential role in skin steroid balance and barrier signalling
  • Protein-based active, biodegradable and biocompatible
  • Low expected systemic exposure at typical formulation levels

Known concerns

  • Limited published cosmetic safety assessment specific to this enzyme
  • Protein actives can theoretically trigger sensitisation in rare cases
  • Stability and activity depend heavily on formulation pH and preservation
  • No CIR or SCCS opinion currently available for this ingredient

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.