IMILOXAN HCL
Other
Avoid
CAS Number: 81167-22-8
About IMILOXAN HCL
Imiloxan Hcl is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Detailed Analysis
Imiloxan hydrochloride is a selective alpha-2 adrenergic antagonist originally developed for peripheral alpha-2 receptor blocking activity. It has been studied in the context of gastrointestinal motility and mast cell stabilisation but has no established cosmetic use. No EU CosIng entry exists, no SCCS review is available, and no CIR assessment exists. The absence of hazard statements and the pharmacological nature of this compound mean it has no demonstrated safety profile for chronic topical cosmetic application. Its receptor-binding activity suggests potential systemic effects if absorbed through skin.
Known Concerns
- ⚠ No EU cosmetic authorisation
- ⚠ Pharmacologically active compound — receptor binding agent
- ⚠ No SCCS or CIR safety assessment available
- ⚠ No safety data for chronic topical exposure
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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