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IODINE

CAS 7553-56-2
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An essential trace element used in cosmetics as an antiseptic agent, but restricted in the EU due to sensitization and regulatory concerns.

Iodine (I2, CAS 7553-56-2) is listed in EU Cosmetics Regulation 1223/2009 Annex II (list of substances prohibited in cosmetic products) under reference II/213, indicating it is restricted in certain cosmetic applications. Free iodine is a known skin sensitizer and can cause allergic contact dermatitis. While iodine is an essential nutrient, its use in cosmetic formulations is strictly regulated. The restriction likely applies to free elemental iodine rather than iodine complexes or iodinated amino acids. Some iodine-releasing compounds may be permitted at specific concentrations.

Skin benefits

  • Antiseptic and antimicrobial properties
  • Used in some acne treatments

Known concerns

  • EU Annex II restricted substance
  • Skin sensitizer and potential allergen
  • Can cause allergic contact dermatitis
  • Excessive use may disrupt thyroid function if absorbed

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.