ISOBUTYL-METHOXYPYRAZINE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
ISOBUTYL-METHOXYPYRAZINE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
Isobutyl-methoxypyrazine is a substituted pyrazine functioning as a fragrance ingredient with powerful green, earthy, and vegetable-like odor characteristics at very low concentrations. Pyrazines in general are known sensitisers at high concentrations, though this specific compound is not listed on EU Annex II or III restrictions. The methoxy and isobutyl substituents increase its lipophilicity and potential for skin penetration, warranting attention to use levels in finished products.
Skin benefits
- Contributes distinctive green, vegetable-like fragrance notes
Known concerns
- Pyrazines can be potent sensitisers at high concentrations
- Powerful odorant requiring very low use levels
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.