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MAO inhibitor antidepressant drug

Isocarboxazid (INN)

CAS 59-63-2
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Isocarboxazid is an irreversible monoamine oxidase inhibitor used as a prescription antidepressant. It has no place in cosmetics due to serious systemic risks and pharmaceutical-only status.

Skin benefits

  • Monoamine oxidase inhibitor used in psychiatry
  • Approved as an antidepressant medicine
  • Of clinical pharmaceutical interest only

Known concerns

  • Prescription antidepressant, not a cosmetic ingredient
  • Serious drug and food interactions including tyramine
  • Hypertensive crisis risk from systemic exposure
  • Hepatotoxicity warnings in product label

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.