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Emollient

ISOCETYL ISOSTEARATE

CAS 52006-45-8
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A branched-chain ester (isocetyl alcohol + isostearic acid) used as a light, silky emollient. Well-tolerated and a workhorse in makeup and lotions.

Isocetyl isostearate (CAS 52006-45-8) is a branched-chain ester combining a 16-carbon iso-alcohol with an 18-carbon iso-fatty acid. The branching gives it a light, dry-feel slip distinct from straight-chain esters, making it popular in color cosmetics, sunscreens, and lightweight lotions. CIR has reviewed alkyl isostearate esters extensively and considers them safe as used in cosmetics. Non-comedogenic at typical use levels (1-15%), low irritation, no sensitization signals in standard testing.

Function

SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING

Skin benefits

  • Lightweight skin softening
  • Disperses pigments evenly
  • Reduces tackiness in oils

Known concerns

  • Cross-reactivity in branched-ester-sensitive users
  • Quality varies with supplier

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related emollients

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.