Other
ISOLEPTOSPERMONE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Isoleptospermone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Isoleptospermone is a naturally occurring sesquiterpene ketone found in Melaleuca alternifolia (tea tree) oil and Corymbia (formerly Eucalyptus) species. It is listed on the EU CosIng database and falls within the category of naturally occurring essential oil constituents subject to allergen declaration requirements. While it contributes to the antimicrobial profile of tea tree oil, isoleptospermone has been identified as a potential contact sensitiser, and the IFRA guidelines restrict its use in leave-on formulations.
Skin benefits
- Antimicrobial properties support preservative function
- Natural origin appeals to clean beauty consumers
Known concerns
- Contact sensitiser potential
- Fragrance allergen requiring declaration under EU law
- Limited long-term sensitisation data
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.