Prohibited pharmaceutical drug
Isometheptene (INN) and its salts
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A sympathomimetic pharmaceutical used for migraine treatment, prohibited from cosmetics in the EU. As an active drug with cardiovascular effects, it has no legitimate role in any personal care formulation.
Skin benefits
- Pharmaceutical sympathomimetic for migraine
- No cosmetic benefit
Known concerns
- Active vasoconstrictor drug, not a cosmetic ingredient
- Cardiovascular and CNS pharmacological effects
- EU Cosmetics Regulation Annex II prohibited
- Drug interaction potential
- Risk of systemic absorption
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.