Isopentyl-4-methoxycinnamate / Amiloxate
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Isopentyl-4-methoxycinnamate / Amiloxate is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.
Amiloxate (Isopentyl-4-methoxycinnamate) is a UV-A filter approved for use in cosmetic sunscreen products within the EU at a maximum concentration of 10%. It effectively absorbs UVA radiation in the 320-360 nm range. However, it is classified as Hazardous to the Aquatic Environment (H400 Very Toxic to aquatic life; H410 Very toxic to aquatic life with long-lasting effects), which has led to regulatory scrutiny. The SCCS has assessed it as safe for cosmetic use at the permitted concentration, but environmental concerns remain.
Skin benefits
- UV-A filter for broad-spectrum sun protection
- Provides photostable UVA absorption
- Used in sunscreen and daily UV-protection products
Known concerns
- H400/H410 - very toxic to aquatic organisms with long-lasting effects
- Environmental concern - contributes to coral reef degradation
- Limited phototoxicity data
- Safe for human use at permitted concentration but ecologically problematic
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.