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ISOPENTYL TRIMETHOXYCINNAMATE TRISILOXANE

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A silicone-based UV filter derived from octinoxate (ethylhexyl methoxycinnamate) modified with trisiloxane, it provides broad-spectrum UV protection but raises concerns about environmental ecotoxicity and potential endocrine-disruptive activity of cinnamate derivatives.

This trisiloxane-modified isopentyl trimethoxycinnamate is a hybrid UV-filter combining a cinnamate-type organic UV absorber with a silicone carrier. Cinnamate UV filters are widely used in sunscreens; however, ethylhexyl methoxycinnamate and related compounds have been flagged in the EU for potential endocrine-disruptive activity and environmental persistence (particularly their toxicity to coral and aquatic organisms). The siloxane modification may improve substantivity but does not resolve underlying cinnamate concerns. It is not currently listed in EU Annexes but is subject to ongoing review.

Skin benefits

  • Provides UV-A and UV-B photoprotection in sunscreen formulations
  • Silicone modification improves water resistance and skin substantivity

Known concerns

  • Cinnamate UV filters under EU review for potential endocrine-disruptive activity
  • Environmental toxicity concerns — ecotoxic to aquatic organisms
  • May cause skin sensitisation in susceptible individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.