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Hair Conditioning

ISOPROPYL CLOPROSTENATE

CAS 157283-66-4 Updated
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A synthetic prostaglandin F2alpha analogue (isopropyl ester of cloprostenol) used in some lash-growth cosmetics. FDA and SCCS treat this class as drug-like, so it does not belong in casual cosmetics.

Skin benefits

  • Marketed in some lash-enhancing serums for eyelash growth

Known concerns

  • Synthetic prostaglandin F2alpha analogue with drug-level activity
  • Reported ocular side effects including iris pigment changes
  • Not approved by FDA as a cosmetic
  • Inadequate cosmetic safety data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.