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Berberine alkaloid derivative

ISOPROPYLBENZYL BUTYLNORBERBERINE IODIDE

40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A quaternized berberine alkaloid iodide salt explored for antimicrobial activity. Iodide content and alkaloid pharmacology raise caution despite the limited safety dossier.

Function

ANTI-SEBORRHEIC, ANTIMICROBIAL, HAIR CONDITIONING

Skin benefits

  • Berberine-derived alkaloid with potential antimicrobial activity
  • May offer anti-inflammatory or sebum-related effects
  • Niche functional active in specialty formulations

Known concerns

  • Iodide salt raises concerns about iodine exposure
  • Berberine derivatives can stain skin and clothing
  • Very limited public safety or efficacy data
  • Alkaloid pharmacological activity warrants caution
  • Not reviewed by CIR or SCCS

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.