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Humectant

ISOSORBIDE

CAS 652-67-5
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A plant-derived sugar alcohol used as a humectant and green solvent. Not classified as a GHS hazard, with broad pharma use as a backbone for nitrate drugs — well-tolerated on skin.

Function

HUMECTANTSKIN CONDITIONING

Skin benefits

  • Bio-based humectant from sorbitol
  • No GHS hazard classification on PubChem
  • Used as a green solvent and skin-conditioner

Known concerns

  • Theoretical mild eye irritation at high % (typical of polyols)
  • Newer in cosmetics, so long-term in-formula data thinner than glycerin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related humectants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.