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botanical diterpenoid active

KIRENOL

CAS 52659-56-0
58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Kirenol is a diterpenoid natural product from Sigesbeckia plants, studied for anti inflammatory and skin soothing effects. It is used as a niche cosmetic active but lacks broad regulatory safety review.

Skin benefits

  • Diterpenoid from Sigesbeckia with anti inflammatory potential
  • Studied for soothing and anti aging skin effects
  • Natural plant derived bioactive
  • Used in some Asian botanical skincare lines

Known concerns

  • No CIR or SCCS opinion specifically on cosmetic use
  • Limited dermal sensitization and irritation data
  • Botanical purity and concentration vary between suppliers
  • Bioactivity at high doses not fully characterized

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.