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LACTASE

85

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An enzyme that breaks down lactose — used in cosmetics as a skin-softening exfoliant that digests dead skin proteins, similar to papain from papaya but from a dairy-free fermentation source.

Lactase (EC 3.2.1.108) is the β-galactosidase enzyme produced through fermentation by Kluyveromyces lactis, a yeast species. It catalyzes the hydrolysis of lactose into glucose and galactose. In cosmetic formulations, proteolytic enzymes like lactase can degrade the protein matrix of dead corneal cells on the skin surface, providing a mild enzymatic exfoliation. The enzyme itself is a protein and carries a risk of provoking immune sensitization if applied to broken skin or inhaled, but is considered safe in rinse-off cosmetic formulations. K. lactis-derived enzymes have GRAS status for food use and no EU restrictions in cosmetics.

Skin benefits

  • Mild enzymatic exfoliation
  • Skin-softening protein digestion
  • Dairy-free enzyme source

Known concerns

  • Potential skin sensitization on broken or compromised skin
  • Immune response possible with protein enzymes
  • Recommended primarily for rinse-off formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.