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Restricted naphthoquinone

LAPACHOL

22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Lapachol is a plant naphthoquinone with antimicrobial activity studied outside cosmetics. The quinone structure carries genotoxicity and reproductive concerns, with no accepted safe role in modern cosmetics.

Skin benefits

  • Naturally derived naphthoquinone from Tabebuia and related trees
  • Studied in non-cosmetic contexts for antimicrobial activity
  • Has historical traditional use outside cosmetics

Known concerns

  • Quinone structure linked to genotoxicity and cytotoxicity concerns
  • Reported reproductive toxicity in animal studies
  • No accepted safe cosmetic use level established
  • Strong staining and irritation potential on skin
  • Restricted or avoided in regulated cosmetic markets

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.