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Penetration enhancer

LAUROCAPRAM

CAS 59227-89-3
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Also known as Azone, this molecule strongly increases skin penetration of cosmetic actives. Strong irritation and corneal cytotoxicity in published studies make it a poor fit for general cosmetic use.

Skin benefits

  • Strong skin penetration enhancer in transdermal formulations
  • Boosts delivery of both polar and non-polar actives

Known concerns

  • Documented strong skin irritant in dermatological studies
  • Cytotoxic to corneal epithelium in published research
  • Penetration enhancement can also drive contaminants deeper into skin
  • Limited cosmetic regulatory acceptance outside niche uses

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.