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LAUROCAPRAM

CAS 59227-89-3
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

LAUROCAPRAM is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Laurocapram (also known as Azone) is a well-known pharmaceutical penetration enhancer used to increase drug flux across skin. While effective at disrupting the stratum corneum lipid matrix, this same mechanism raises concern for cosmetic use, as chronic disruption of the skin barrier may lead to irritation, sensitization, and increased systemic absorption of other formulation ingredients.

Skin benefits

  • Potent penetration enhancer that can increase delivery of actives into skin

Known concerns

  • Disrupts stratum corneum lipid barrier structure
  • Limited long-term safety data for repeated cosmetic use
  • May increase absorption of unwanted cosmetic or environmental chemicals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.