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LIDOCAINE

CAS 137-58-6
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A local anesthetic restricted in EU cosmetics due to its pharmacological action, and its use in cosmetic products is prohibited.

Lidocaine is a local anesthetic (amide-type) that works by blocking sodium channels in nerve endings, producing temporary numbness. It is listed in EU Annex II (entry II/399) under Regulation (EC) No 1223/2009, which prohibits its use in cosmetic products. Its pharmacological activity and potential for systemic absorption make it unsuitable for unsupervised cosmetic use, though it remains widely used in medically supervised contexts such as dermal procedures.

Known concerns

  • EU Annex II prohibited substance — banned in cosmetic products
  • Pharmacological activity with potential systemic absorption
  • Can cause allergic contact dermatitis in sensitized individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.