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Hair dye intermediate salt

M-PHENYLENEDIAMINE SULFATE

CAS 541-70-8
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

The sulfate salt of m-phenylenediamine carries the same EU prohibition as its parent. It is not permitted in cosmetics due to documented sensitization, mutagenicity, and carcinogenicity concerns.

Skin benefits

  • Sulfate salt historically used as oxidative hair dye precursor
  • Improved solubility versus free base
  • Produced dark color shades in permanent hair color

Known concerns

  • Salt of EU-prohibited m-phenylenediamine, sharing same toxicity profile
  • Strong sensitizer and suspected genotoxin
  • Banned in EU cosmetics under Annex II
  • Cross-reactivity with other phenylenediamine dyes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.