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Industrial isocyanate

m-Tolylidene diisocyanate (Toluene diisocyanate)

CAS 26471-62-5
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Toluene diisocyanate is a highly reactive industrial isocyanate used in polyurethane production. It is a potent respiratory sensitizer, suspected carcinogen, and corrosive material with no place in cosmetic formulations.

Skin benefits

  • Industrial chemical used in polyurethane manufacture
  • Not a cosmetic ingredient
  • Useful in foam and coating chemistry

Known concerns

  • Classified as IARC Group 2B possibly carcinogenic to humans
  • Severe respiratory sensitizer causing occupational asthma
  • Skin and eye corrosive
  • Absolutely not appropriate for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.