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Skin Conditioning

MADECASSIC ACID

CAS 18449-41-7
84

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Centella asiatica triterpenoid — a key skin-soothing and barrier-supporting active. Strong reputation in cica products with very low irritation profile.

Function

SKIN CONDITIONING

Skin benefits

  • Centella triterpenoid soothing active
  • Wound-healing and barrier support
  • Anti-inflammatory
  • Antioxidant

Known concerns

  • Rare individual sensitivity
  • Limited GHS data — niche pharmacology
  • Concentration-dependent activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.