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Antimicrobial

MAFENIDE HCL

CAS 138-37-4 Updated
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A prescription sulfonamide antibacterial drug used on burns, not a typical cosmetic. Carries sulfa-allergy and metabolic-acidosis risks; should not appear in regular skincare.

Function

ANTIMICROBIAL

Skin benefits

  • Bacteriostatic against gram-positive and gram-negative bacteria
  • Established medical use in burn therapy

Known concerns

  • Prescription topical sulfonamide drug, not a true cosmetic
  • Risk of sulfonamide allergic reactions
  • Systemic absorption can trigger metabolic acidosis
  • Inappropriate for OTC personal-care formulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.