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Maleic hydrazide [ISO]

CAS 123-33-1
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Maleic Hydrazide [iso] is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Maleic hydrazide is an ISO-named plant growth regulator used in agriculture that is not approved for cosmetic use under EU Cosmetics Regulation (EC) No 1223/2009. While it has been evaluated by regulatory bodies and has a WHO/FAO acceptable daily intake for food residues, its classification as a Category 2 suspected carcinogen under EU CLP Regulation (H351) and lack of any cosmetic necessity means it should not appear in cosmetic formulations. IARC has classified it as Group 3 (not classifiable as to carcinogenicity to humans), which is less severe than many other pesticides on this list.

Known concerns

  • Suspected carcinogen (EU CLP Category 2, H351)
  • Not approved for cosmetic use in the EU
  • Limited data on skin sensitization and long-term topical exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.