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Mineral / antioxidant cofactor

MANGANESE GLYCINATE

CAS 14281-77-7
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Manganese glycinate is a chelated form of manganese that supplies trace amounts of this mineral cofactor to skin antioxidant enzymes. It is more familiar as a dietary supplement than a topical cosmetic ingredient.

Skin benefits

  • Provides manganese in a chelated, bioavailable form
  • Manganese is a cofactor for skin antioxidant enzymes such as MnSOD
  • May support antioxidant defences when used at trace levels

Known concerns

  • High manganese exposure is neurotoxic, so concentration matters
  • Limited cosmetic-specific safety review for topical use
  • Could stain or interact with other ingredients at higher levels

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.