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Skin Conditioning

MATRINE COCOATE

Updated
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A salt of matrine — an alkaloid from Sophora root — paired with coconut fatty acid. The alkaloid component is bioactive but matrine has documented hepatotoxicity in oral pharma use, lowering the cosmetic safety margin.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Reported anti-inflammatory activity from matrine moiety
  • Botanical alkaloid with antimicrobial potential
  • Mild surfactant character from cocoate

Known concerns

  • Matrine alkaloid has hepatotoxicity risk at higher exposures
  • Limited cosmetic safety data for the salt form
  • Bitter alkaloids carry skin sensitization potential

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.